Whole venom of Loxosceles similis activates caspases-3, -6, -7, and -9 in human primary skin fibroblasts
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چکیده
منابع مشابه
Peroxynitrite activates the phosphoinositide 3-kinase/Akt pathway in human skin primary fibroblasts.
Peroxynitrite is a potent oxidizing and nitrating species formed in a diffusion-limited reaction between nitrogen monoxide and superoxide. It induces apoptosis through unknown mechanisms and is believed to interfere with receptor tyrosine kinase signalling through nitration of tyrosine residues. One pathway emanating from receptor tyrosine kinases is that leading to activation of the anti-apopt...
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ژورنال
عنوان ژورنال: Toxicon
سال: 2014
ISSN: 0041-0101
DOI: 10.1016/j.toxicon.2014.04.002